La Libre Belgique special edition on cancer

Prof. Blanpain makes the cover of this special edition PDF

An EMBO long-term fellowship for Magdalena Sznurkowska

Magdalena Sznurkowska has been working in the lab as a post-doctoral researcher for one year.  The fellowship she received from EMBO, a prestigious organization of more than 1800 leading researchers that promotes excellence in the life sciences, will permit her to carry on her research on the cellular and molecular basis of cancer metastasis. 

World Cancer Day : a new campaign for Télévie

In the distant future, will cancer still be so frightening?  Will it be easily and totally curable?  Prof. Blanpain has accepted to answer these questions for the new Télévie campaign.  PDF

Joint interview with Jean Stéphenne and Cédric Blanpain

Is the creation of biotech companies as a logical extension of scientific research work worthwhile?  Read under the link below the viewpoints of Jean Stéphenne, former GlaxoSmithKline CEO and Prof. Cédric Blanpain.

“Il nous faut des chercheurs qui puissent écouter”, L’Echo, 10 December 2018.  PDF

 

Publication in Nature 2018: Overcoming the resistance to therapy in skin cancer

Sánchez-Danés A, Larsimont JC, Liagre M, Muñoz-Couselo E, Lapouge G, Brisebarre A, Dubois C, Suppa M, Sukumaran V, Del Marmol V, Tabernero J,Blanpain C.A
Slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy.
Nature. 2018 Oct; 562(7727):434-438. doi: 10.1038/s41586-018-0603-3. Epub 2018 Oct 8.
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Cédric Blanpain cited as a good incarnation of leadership in Wallonia

“Des fêtes dans une Wallonie en panne de leadership”, Le Soir, 15-16 September 2018.   PDF

A long portrait of Cédric Blanpain au «Soir» : « J’ai peur du cancer donc je cherche à le soigner »

In the framework of its summer series, Le Soir publishes a long portrait of Prof. Cédric Blanpain : « Mon moteur?  La découverte de l’inconnu »,  11 August 2018. PDF

Launch of ChromaCure SA (Belgium)

This new spin-off will be dedicated to the development of therapeutic molecules against cancer.  The launch of this very promising venture is considered a major event in the Belgian biotech world. 

« Cédric Blanpain lève 17 millions contre le cancer », L’Echo, 30 may 2018.   PDF

Publication in Nature Cell Biology 2018: Origin of mammary gland stem cells identified

Wuidart A, Sifrim A, Matsumura S, Fioramonti M, Brisebarre A, Brown D , Centonze A, Dannau A, Dubois C, Van Keymeulen A, Voet T, Blanpain C
Early lineage segregation of multipotent embryonic mammary gland progenitors.
Nat Cell Biol.2018 Jun;20(6):666-676. doi: 10.1038/s41556-018-0095-2. Epub 2018 May 21.
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Publication in Nature 2018: Tumor transition state and the origin of the metastasis

Pastushenko I, Brisebarre A, Sifrim A, Fioramonti M, Renvenco T, Boumahdi S, Van Keymeulen A, Brown D, Moers V, Lemaire S, De Clercq S, Minguijon E, Cédric Balsat C, Sokolow Y, Dubois C, de Cock F, Scozzaro S, Sopena F, Lanas A, D’Haene N, Salmon I, Marine JC, Voet T, Sotiropoulou P and Blanpain C.
Identification of the tumour transition states occurring during EMT.
Nature. 2018 Apr;556(7702):463-468. doi: 10.1038/s41586-018-0040-3. Epub 2018 Apr 18.
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Publication in Science 2018: Early step of cardiac development revealed

Lescroart F, Wang X, Lin X, Swedlund B, Gargouri S, Sànchez-Dànes A, Moignard V, Dubois C, Paulissen C, Kinston S, Göttgens B,Blanpain C.
Defining the earliest step of cardiovascular lineage segregation during gastrulation by single cell RNA-seq.
Science. 2018 Mar 9;359(6380):1177-1181. doi: 10.1126/science.aao4174. Epub 2018 Jan 25.
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Belgian Foundation against Cancer Research Award to Prof. Blanpain

The Belgian Foundation against Cancer has granted its first Cancer Research Award to Prof. Blanpain in the field of fundamental research.  This award is given to the researcher who has been ranked in first place in the grant selection.  Press release

Publication in Cell Stem Cell 2016/2017. The origin of EMT revealed

Latil M, Nassar D, Beck B, Boumahdi S, Wang L, Brisebarre A, Dubois C, Nkusi E, Lenglez S, Checinska A, Vercauteren Drubbel A, Devos M, Declercq W, Yi R, Blanpain C.
Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition. Cell Stem Cell.2017 Feb 2;20(2):191-204.e5. doi:10.1016/j.stem.2016.10.018. Epub 2016 Nov 23.
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Prof. Cédric Blanpain elected as a member of Academia Europaea

Founded in 1988, Academia Europaea is a European, non-governmental association acting as an Academy.  Its 3800 members are scientists and scholars who collectively aim to promote learning, education and research.   Academia Europaea supports  the advancement and propagation of excellence in scholarship anywhere in the world.

Publication in Nature 2016: The origin of skin cancer uncovered

Sánchez-Danés A, Hannezo E, Larsimont JC, Liagre M, Youssef KK, Simons B, Blanpain C.Defining the clonal dynamics leading to mouse skin tumor initiationNature. 2016 Aug 18;536(7616):298-303. Epub 2016 Jul 8.

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Publication in Cell Reports : Researchers at the Université libre de Bruxelles, ULB uncover the number and clonal dynamics of cardiac progenitors during heart morphogenesis

Chabab S, Lescroart F, Rulands S, Mathiah N, Simons BD and Blanpain C.
Uncovering the number and clonal dynamics of Mesp1 progenitors during heart morphogenesis.
Cell Reports 2016 Jan 5;14(1):1-10. doi: 10.1016/j.celrep.2015.12.013. Epub 2015 Dec 24.
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Pr. Cédric Blanpain received from his Majesty the King Philippe the prestigious prize “Prix Quinquennal, – Prix Joseph Maisin”

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Publication in Nature Cell Biology : researchers at the Université Libre de Bruxelles, ULB show the causal link between aneuploidy and cancer

Sercin O., Larsimont J.C., Karambelas A.E., Marthiens V., Moers V., Boeckx B., e Mercier M., Lambrechts D., Basto R., Blanpain C.
Nature Cell Biology, 2016 Jan;18(1):100-10. doi: 10.1038/ncb3270. Epub 2015 Nov 23.
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Publication in Nature: researchers at the Université Libre de Bruxelles, ULB identify the cells at the origin of breast cancers

Van Keymeulen A, Lee M.Y., Ousset M, Rorive S, Brohée S, Wuidart A, Bouvencourt G, Giraddi R, Dubois C, Salmon I, Sotiriou C, Phillips W.A., Blanpain C.
Reactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity.
Nature 2015  Sep 3;525(7567):119-23. doi: 10.1038/nature14665. Epub 2015 Aug 12.
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Publication in Nature Medicine: Researchers at the Université libre de Bruxelles (ULB), KU Leuven and VIB uncover new genetic alterations involved in the development of skin squamous cell carcinoma

Nassar D, Latil M, Boeckx B, Lambrechts D, Blanpain C.
Genomic landscape of carcinogen and gentically-induced mouse skin squamous cell carcinoma.
Nat Med. 2015 Aug;21(8):946-54. doi: 10.1038/nm.3878. Epub 2015 Jul 13.
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Mariaceleste ARAGONA received the Human Frontier Science Program (HFSP) fellowship award

HFSP 2015 Awardees

Pr. Cédric Blanpain received the “Convention d’Excellence” grant from the Fonds Erasme

Fonds Erasme

Maylis RAPHAEL obtained a EMBO (European Molecular Biology Organization) Long-term Fellowship

Publication in Cell Stem Cell : Researchers at the Université libre de Bruxelles, ULB uncover a new mechanism involved in tumour initiation, growth and progression in skin squamous cell carcinoma

Beck B, Lapouge G, Rorive S, Drogat B, Desaedelaere K, Delafaille S, Dubois C, Salmon I, Willekens K, Marine JC, Blanpain C.
Different levels of Twist1 regulate skin tumor initiation, stemness, and progression.
Cell Stem Cell. 2015 Jan 8;16(1):67-79. doi: 10.1016/j.stem.2014.12.002.
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Publication in Nature Cell Biology: Researchers at the Université libre de Bruxelles defined the early lineage segregation during early mammalian heart development. Lescroart et al

Lescroart F, Chabab S, Lin X, Rulands S, Paulissen C, Rodolosse A, Auer H, Achouri Y, Dubois C, Bondue A, Simons BD, Blanpain C.
Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development.
Nat Cell Biol. 2014 Sep;16(9):829-40. doi: 10.1038/ncb3024. Epub 2014 Aug 24.
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Publication in Nature: Researchers at the Université libre de Bruxelles uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma. Boumhadi et al

Publication in Nature: Researchers at the Université libre de Bruxelles uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma. Boumhadi et al

Boumahdi S, Driessens G, Lapouge G, Rorive S, Nassar D, Le Mercier M, Delatte B, Caauwe A, Lenglez S, Nkusi E, Brohée S, Salmon I, Dubois C, del Marmol V, Fuks F, Beck B, Blanpain C.
SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
Nature. 2014 Jul 10;511(7508):246-50. doi: 10.1038/nature13305. Epub 2014 Jun 8.
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Mathilde Latil received the “Prix pour les Jeunes Chercheurs” award from the Bettencourt-Schuller Foundation

“Prix pour les Jeunes Chercheurs” Bettencourt-Schuller Foundation

Publication in Nature Cell Biology: Researchers at the Université Libre de Bruxelles, uncover the molecular mechanisms leading to basal cell carcinoma initiation. Kass Youssef et al

Publication in Nature Cell Biology: Researchers at the Université Libre de Bruxelles, uncover the molecular mechanisms leading to basal cell carcinoma initiation. Kass Youssef et al

Youssef KK, Lapouge G, Bouvrée K, Rorive S, Brohée S, Appelstein O, Larsimont JC, Sukumaran V, Van de Sande B, Pucci D, Dekoninck S, Berthe JV, Aerts S, Salmon I, del Marmol V, Blanpain C.
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation.
Nat Cell Biol. 2012 Dec;14(12):1282-94. doi: 10.1038/ncb2628. Epub 2012 Nov 25.
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Fabienne Lescroart received the “Prix pour les Jeunes Chercheurs” award from the Bettencourt-Schuller Foundation.

“Prix pour les Jeunes Chercheurs” Bettencourt-Schuller Foundation

Interview with Pr. Cédric Blanpain by the Association for International Cancer Research (AICR)

http://www.aicr.org.uk Association for International Cancer Research (AICR)

AICR Interview Dr Cedric Blanpain, ULB, talks to the Association for International Cancer Research about joining the Scientific Advisory Committee.

Publication in Nature Cell Biology: Researchers at the Université Libre de Bruxelles, ULB identify multipotent and unipotent Stem Cells (SCs) that contribute to prostate postnatal development. Ousset et al.

Publication in Nature Cell Biology: Researchers at the Université Libre de Bruxelles, ULB identify multipotent and unipotent Stem Cells (SCs) that contribute to prostate postnatal development. Ousset et al.

Ousset M, Van Keymeulen A, Bouvencourt G, Sharma N, Achouri Y, Simons BD, Blanpain C.
Multipotent and unipotent progenitors contribute to prostate postnatal development.
Nat Cell Biol. 2012 Oct 14. doi: 10.1038/ncb2600. [Epub ahead of print]
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Cancer Stem Cell Course by Pr. Jacques Boniver and Pr. Cédric Blanpain – Collège de Belgique

Online Course